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COMPARATIVE STUDY OF ANTI-HISTAMINIC & ANTIINFLAMMATORY ACTIVITY OF TALISADI CHOORNA & GUTI CONTAINING SYNTHETIC VANSHLOCHAN
COMPARATIVE STUDY OF ANTI-HISTAMINIC & ANTIINFLAMMATORY ACTIVITY OF TALISADI CHOORNA & GUTI CONTAINING SYNTHETIC VANSHLOCHAN
WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES
SJIF Impact Factor 6.647 Volume 6, Issue 2, 1206-1218 Research Article ISSN 2278 – 4357
Dr. Atul Gaikwad1* and Dr. Nandini More2
1Assistant Professor, Department of Rasashastra & Bhaishajyakalpana Vigyan, College of Ayurved, Bharati Vidyapeeth Deemed University, Dhankawadi, Pune-411043. 2Associate Professor, Department of Rasashastra & Bhaishajyakalpana Vigyan, College of Ayurved, Bharati Vidyapeeth Deemed University, Dhankawadi, Pune-411043.
ABSTRACT Shwas is a disease of pranvaha srotas, which can be co-related with Asthma. Histamine and submucosal inflammation are counted among the causative factors of Asthma. Thus, for a formulation to be effective in Asthma, has to possess both anti-histaminic and anti-inflammatory activity. In the present study Anti-Histaminic activity was evaluated using‘Protection against histamine induced bronchospasm’ model and Anti-Inflammatory activity was evaluated using‘Cotton wool Granuloma’ model. From this study it is evident that Talisadi Choorna and Guti both have significant Anti-Histaminic and Anti-Inflammatory activity. When both the activities of Talisadi Choorna and Guti were compared, no significant difference in efficacy was observed.
WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES
SJIF Impact Factor 6.647 Volume 6, Issue 2, 1206-1218 Research Article ISSN 2278 – 4357
Dr. Atul Gaikwad1* and Dr. Nandini More2
1Assistant Professor, Department of Rasashastra & Bhaishajyakalpana Vigyan, College of Ayurved, Bharati Vidyapeeth Deemed University, Dhankawadi, Pune-411043. 2Associate Professor, Department of Rasashastra & Bhaishajyakalpana Vigyan, College of Ayurved, Bharati Vidyapeeth Deemed University, Dhankawadi, Pune-411043.
ABSTRACT Shwas is a disease of pranvaha srotas, which can be co-related with Asthma. Histamine and submucosal inflammation are counted among the causative factors of Asthma. Thus, for a formulation to be effective in Asthma, has to possess both anti-histaminic and anti-inflammatory activity. In the present study Anti-Histaminic activity was evaluated using‘Protection against histamine induced bronchospasm’ model and Anti-Inflammatory activity was evaluated using‘Cotton wool Granuloma’ model. From this study it is evident that Talisadi Choorna and Guti both have significant Anti-Histaminic and Anti-Inflammatory activity. When both the activities of Talisadi Choorna and Guti were compared, no significant difference in efficacy was observed.
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